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Dog Health...Masticatory Muscle Myositis Dog HealthMasticatory Muscle Myositis Masticatory Muscle Myositis (MMM) is an inflammatory disease in dogs affecting the muscles of the jaw. Signs include swelling of the jaw muscles and pain on opening the mouth. In chronic MMM there is atrophy of the jaw muscles, and scarring of the masticatory muscles due to fibrosis may result in inability to open the mouth (trismus). Masticatory muscle myositis (MMM) is an inflammatory disease in dogs affecting the muscles of mastication (chewing). It is also known as atrophic myositis or eosinophilic myositis. MMM is the most common inflammatory myopathy in dogs. The disease mainly affects large breed dogs. German Shepherd Dogs and Cavalier King Charles Spaniels may be predisposed. There is a similar disease of the eye muscles found in Golden Retrievers. Symptoms of acute MMM include swelling of the jaw muscles, drooling, and pain on opening the mouth. Ophthalmic signs may include third eyelid protrusion, red eyes, and exophthalmos (protruding eyeballs). In chronic MMM there is atrophy of the jaw muscles, and scarring of the masticatory muscles due to fibrosis may result in inability to open the mouth (trismus). The affected muscles include the temporalis, masseter, and pterygoid muscles. The disease is usually bilateral. MMM is caused by the presence of 2M fibers in the muscles of the jaw. 2M fibers are not found elsewhere in the body, but they are close in structure to proteins found on the surface of bacteria. The immune system recognizes these proteins as foreign to the body and attacks them, resulting in inflammation. Diagnosis of MMM is through either biopsy of the temporalis or masseter muscles or the 2M antibody assay, in which blood serum of the possible MMM-dog is reacted with temporalis tissue of a normal dog, or both. False negatives by the 2M antibody assay may be obtained if MMM is end-stage with destruction of type 2M fibers and marked fibrosis. Treatment is usually with corticosteroids such as prednisone, often with decreasing doses for up to 4–6 months, and in the case of trismus, manual opening of the mouth under anesthesia. Feeding very soft or liquid food during this time is usually necessary. The ultimate degree of recovery of jaw function and muscle mass will depend upon the extent of damage to the muscle tissue. Recurrence of MMM may occur. Misdiagnosis of MMM as a retroorbital abscess based on physical examination and finding of trismus leads to inappropriate treatment with antibiotics, which will not impede the progress of MMM. from: wikipedia The dog disease directory at Long Live Puppies is a list of diseases and other health conditions related to dogs and are continuously being updated with new definitions and improvements. A happy and healthy pet contributes to your own health and happiness. The articles here are constructed to help aide you in making informative decisions concerning your puppy and dog and your family. The intentions of these articles are to help give you choices on how to find your puppy, topics of discussions with family members before the decision to get a dog is set in stone, how to prepare your home for him, how to care for him throughout his life and how to spend quality, enjoyable time with him. Any medical advice or health information should never take the place of your veterinarian. If your dog is not feeling well or there is something wrong, don’t wait! Make a doctor’s appointment with your veterinarian as soon as possible. We welcome any suggestions to our articles. Our contributors are working hard to bring you the most up-to-date quality information. Complete Dog Disease Directory Dog Skeletal/Muscular Disorders - Masticatory Muscle Myositis (MMM) - Dog Health Issues Dog Health Masticatory Muscle Myositis Dog related information, articles and descriptive, educational videosincluding related dog skeletal/muscular disorders - masticatory muscle myositis (mmm) - dog health issues videos when possible

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