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Dog Health...Osteosarcoma Dog HealthOsteosarcoma Osteosarcoma is an aggressive cancerous neoplasm arising from primitive transformed cells of mesenchymal origin that exhibit osteoblastic differentiation and produce malignant osteoid. Osteosarcoma is the most common bone tumor in dogs and typically afflicts middle-age large and giant breed dogs such as Irish Wolfhounds, Greyhounds, German Shepherds, Rottweilers, mountain breeds (great Pyrenees, St. Bernard, Leonberger, Newfoundland), Doberman Pinschers and Great Danes. It has a ten times greater incidence in dogs than humans. A hereditary base has been shown in St. Bernard dogs. Spayed/neutered dogs have twice the risk of intact ones to develop osteosarcoma. Infestation with the parasite Spirocerca lupi can cause osteosarcoma of the esophagus. Treatment: Amputation of the leg is the initial treatment, although this alone will not prevent metastasis. Chemotherapy combined with amputation improves the survival time, but most dogs still die within a year. There are surgical techniques designed to save the leg (limb-sparing procedures), but they do not improve the prognosis. One key difference between osteosarcoma in dogs and humans is that the cancer is far more likely to spread to the lungs in dogs. Some current studies indicate that osteoclast inhibitors such as alendronate and pamidronate may have beneficial effects on the quality of life by reducing osteolysis, thus reducing the degree of pain as well as the risk of pathological fractures. from: wikipedia The dog disease directory at Long Live Puppies is a list of diseases and other health conditions related to dogs and are continuously being updated with new definitions and improvements. A happy and healthy pet contributes to your own health and happiness. The articles here are constructed to help aide you in making informative decisions concerning your puppy and dog and your family. The intentions of these articles are to help give you choices on how to find your puppy, topics of discussions with family members before the decision to get a dog is set in stone, how to prepare your home for him, how to care for him throughout his life and how to spend quality, enjoyable time with him. Any medical advice or health information should never take the place of your veterinarian. If your dog is not feeling well or there is something wrong, don’t wait! Make a doctor’s appointment with your veterinarian as soon as possible. We welcome any suggestions to our articles. Our contributors are working hard to bring you the most up-to-date quality information. Complete Dog Disease Directory Dog Cancer Health Disorders - Osteosarcoma - Dog Health Issues Dog Health Osteosarcoma Dog related information, articles and descriptive, educational videosincluding related dog cancer health disorders - osteosarcoma - dog health issues videos when possible

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